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1.
Indian J Pathol Microbiol ; 64(2): 334-338, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33851629

RESUMO

Intraosseous hemangiomas are uncommon, constituting less than 1% of all osseous tumors. The most frequent sites are the calvaria and the vertebral column. The involvement of the facial bones is rare, and if occurs, it can involve maxilla, mandible, nasal bones and zygomatic bone. Zygomatic hemangioma is a benign, slow-growing tumor occurring mostly in adult women. The radiographic findings are diagnostic. Total excision of the tumor with the primary reconstruction of the defect is the preferred treatment modality. Here, we are reporting a case of a 37-year-old woman who presented with a painless hard swelling in the right zygomatic prominence, which was diagnosed as intraosseous hemangioma after the radiological examination because of its characteristic radiological picture. An Excisional biopsy also proved the swelling to be a cavernous hemangioma.


Assuntos
Hemangioma Cavernoso/patologia , Neoplasias Cranianas/patologia , Crânio/anormalidades , Coluna Vertebral/anormalidades , Malformações Vasculares/patologia , Zigoma/irrigação sanguínea , Zigoma/patologia , Adulto , Feminino , Hemangioma Cavernoso/cirurgia , Humanos , Crânio/patologia , Coluna Vertebral/patologia , Tomografia Computadorizada por Raios X , Zigoma/cirurgia
2.
Asian Pac J Cancer Prev ; 21(4): 1163-1166, 2020 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-32334486

RESUMO

BACKGROUND: Early detection of oral cancer is of critical importance because survival rates markedly improve when oral lesions are identified at an early stage. Aim of the present study is to investigate the expression of ABO (H) antigens in tissue specimens of oral cancer and potentially malignant disorders and to determine the role of ABO (H) antigens in tumour staging. MATERIALS AND METHODS: A prospective study was conducted on 60 cases of oral cancer and potentially malignant diseases. Specific red cell adherence test (SRCA-test) was used for studying A, B and O (H) antigens in tissue specimens and iso-antigenicity of epithelium was graded according to degree of adherence of indicator red blood cells. RESULTS: Among OSMF group, grade II adherence was seen in 53.3% cases, grade III in 33.3% cases, grade IV in 13.3% cases. In leukoplakia group, grade II adherence was seen in 26.7% cases, grade III adherence in 53.3% cases, grade IV adherence in 20% cases. Within the leukoplakia group, cases with dysplasia showed decreased adherence, compared with cases without dysplasia. Oral cancer group, negative adherence was seen in 13.3% cases, grade I adherence in 46.7% cases, grade II in 40% cases. In oral cancer group, antigen reactivity was less in poorly and moderately differentiated carcinoma, compared to well differentiated carcinoma. CONCLUSIONS: Antigen adherence and degree of loss of ABO (H) antigens in tissue specimens can be used for staging of the tumour.


Assuntos
Sistema ABO de Grupos Sanguíneos/sangue , Biomarcadores Tumorais/sangue , Carcinoma de Células Escamosas/diagnóstico , Leucoplasia Oral/diagnóstico , Neoplasias Bucais/diagnóstico , Fibrose Oral Submucosa/diagnóstico , Sistema ABO de Grupos Sanguíneos/imunologia , Biomarcadores Tumorais/imunologia , Carcinoma de Células Escamosas/sangue , Carcinoma de Células Escamosas/imunologia , Seguimentos , Humanos , Leucoplasia Oral/sangue , Leucoplasia Oral/imunologia , Neoplasias Bucais/sangue , Neoplasias Bucais/imunologia , Fibrose Oral Submucosa/sangue , Fibrose Oral Submucosa/imunologia , Prognóstico , Estudos Prospectivos
3.
J Cancer Res Ther ; 14(2): 394-397, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29516926

RESUMO

BACKGROUND AND OBJECTIVES: To evaluate the efficacy of ultrasonography (USG) as a noninvasive tool in assessing the severity of oral submucous fibrosis (OSMF) by measuring the submucosal thickness and also to correlate the sonographic changes with clinical staging. MATERIALS AND METHODS: The submucosal thickness of the upper and lower labial mucosa, anterior and posterior portions of the right and left buccal mucosa were measured using ultrasound in 64 patients comprising of 32 OSMF patients and 32 controls. Among the controls, 16 were with a habit of chewing gutkha and 16 were without any habit history. RESULTS: In OSMF group, four patients were with Stage I, 13 were with Stage II, 11 were with Stage III, and four with Stage IV. Results were analyzed by one-way analysis of variance for the significance of difference among the groups in submucosal thickness. As the stages of OSMF advanced, there was an increase in submucosal thickness of the buccal mucosa in the study group when compared with controls (P< 0.005). CONCLUSION: USG is an effective noninvasive zero radiation tool for assessing the progression of OSMF.


Assuntos
Carcinoma de Células Escamosas/diagnóstico por imagem , Mucosa Bucal/patologia , Fibrose Oral Submucosa/diagnóstico por imagem , Fibrose Oral Submucosa/patologia , Ultrassonografia , Carcinoma de Células Escamosas/etiologia , Carcinoma de Células Escamosas/patologia , Estudos de Casos e Controles , Feminino , Hábitos , Humanos , Masculino , Estadiamento de Neoplasias , Fibrose Oral Submucosa/etiologia , Lesões Pré-Cancerosas/diagnóstico por imagem , Lesões Pré-Cancerosas/patologia , Índice de Gravidade de Doença , Ultrassonografia/métodos
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